International Journal of Applied Research
Vol. 5, Issue 1, Part E (2019)
Effects of ibuprofen and diclofenac potassium on blood coagulation tests after periodontal surgery
Non-steroidal anti-inflammatory drugs are potent analgesics, anti-inflammatory and ant-pyretic agents. These drugs are potent inhibitors of the cyclooxygenase enzymes within the platelets. This inhibition blocks the production of thromboxane (TXA2), which increases the risk of prolonged bleeding. Platelet aggregation by NSAIDs is reversible, but the effect depends on the dosage and duration of therapy, serum levels, half-life, and simultaneous use of anticoagulants or alcohol. This study was therefore done to assess and compare the effects of the most commonly used NSAIDs; ibuprofen and diclofenac potassium on bleeding after periodontal surgery.
How to cite this article:
Dr. Anas Abdul Khader, Dr. Vino Tito V Kurien, Dr. Shashikanth Hegde, Dr. Rajesh Kashyap Shanker, Dr. Maiya Arun Kumar. Effects of ibuprofen and diclofenac potassium on blood coagulation tests after periodontal surgery. Int J Appl Res 2019;5(1):329-332.