Vol. 5, Special Issue 4, Part J (2019)

Results: The basal heart rates are comparable between the two groups and the difference is not statistically significant. There is a statistically significant difference between the two groups after starting loading dose infusion and induction, where in statistically significant fall in HR is noted in group DX. But after laryngoscopy and intubation there is increase in heart rate in both groups which more in group NG compared to group DX (P<0.001). The intraoperative mean HR during surgery is significantly lower in group DX compared to group NG (P<0.001). At 15 min minutes there is no significant difference in the 2 groups with respect to the average surgical field grading of each study population. At 30 min there is significant difference between 2 groups with group DX having average surgical field grade of 1.88±0.52, which is less compared to that of group NG, 2.54±0.49 (P<0.001). The average intraoperative surgical field grade was 2.18±o.51 in group DX, which was significantly better than 2.41±0.61 in group NG (p=0.29).

Conclusion: Dexmedetomidine and Nitroglycerine both can be used with great safety profile to achieve controlled hypotension during spine surgeries.