Vol. 5, Issue 5, Part D (2019)
Bacteriological profile and antibiogram of wound infection in a tertiary care hospital
Bacteriological profile and antibiogram of wound infection in a tertiary care hospital
Author(s)
Dr. SK Sathiya Priya
AbstractIntroduction: Wound infection is one of the most important cause of morbidity and mortality worldwide and antibiotic resistant bacteria are the great part of complications on treatment of infections.
Objectives: The present study was conducted to isolate and identify the bacterial pathogens causing wound infections and their antibiotic susceptibility pattern.
Materials and Methods: A total of 168 pus samples were collected from patients with wound infections over a period of six months. Samples were collected, transported and processed in the laboratory as per standard protocol. Antibiotic susceptibility test was done by Kirby Bauer disc diffusion method.
Results: Out of 168 samples, 129(76.8%) yielded growth and 39(23.2%) yielded no growth. The most predominant Gram positive cocci isolated was Staphylococcus aureus 36(27.91%) and among the gram negative bacteria E.coli 23(17.83%) was most commonly isolated. The gram positive cocci were mostly sensitive to Vancomycin (100%) and Linezolid (100%). Among the gram negative isolates, Pseudomonas aeuroginosa were mostly sensitive to Meropenem (100%), Aztreonam (100%) and Piperacillin-Tazobactum (100%). E.coli and Proteus sp. were sensitive to Amikacin and Gentamycin.
Conclusion: The present study concludes the isolation rate of Staphylococcus aureus was the highest. The most effective drugs for Gram positive isolates were found to be Linezolid and Vancomycin. The gram negative isolates were mostly sensitive to Amikacin and Gentamycin. The change in the pattern of bacterial resistance towards the common antibiotics occurs time to time which may lead to resistance to broad spectrum antibiotics. Hence it is important to monitor bacterial susceptibility to antibiotics in wound infections to limit the emergence and spread of these pathogens.
How to cite this article:
Dr. SK Sathiya Priya. Bacteriological profile and antibiogram of wound infection in a tertiary care hospital. Int J Appl Res 2019;5(5):201-203.