International Journal of Applied Research
Vol. 6, Issue 10, Part M (2020)
Performance of an immunochromatographic assay for rapid diagnosis of scrub typhus in an outlying health care facility
c There is a need for rapid and easy to perform diagnostic test as Scrub Typhus is commonly found in persons working in marshy land and dwelling in areas away from health care facilities. Rapid diagnosis initiates early and specific treatment.
Material and Methods: A total of 93 serum samples collected from patients residing in considerably secluded area of Vidarbha in Maharashtra were tested in State Surveillance Laboratory (SSL) by immunochromatographic SD Bioline test (ICT-SD Bioline) for the diagnosis of Scrub Typhus. The test was evaluated using IgM ELISA as reference test.
Results: In absence of a perfect reference test for Scrub Typhus, evaluation of ICT-SD Bioline using IgM ELISA as a reference test gave a sensitivity of 98.57% and a specificity of 92.31%.
Conclusion: ICT-SD Bioline gave a high sensitivity but since duration of fever prior to testing was not taken into account, its ability to react in presence of disease with high probability to warranted. However its high specificity definitely affirms the presence of disease with high probability.
How to cite this article:
Dr. Swati M. Bhise, Dr. Pooja D. Taiwade,, Dr. Vandana A. Agarwal. Performance of an immunochromatographic assay for rapid diagnosis of scrub typhus in an outlying health care facility. Int J Appl Res 2020;6(10):794-796.