International Journal of Applied Research
Vol. 6, Issue 3, Part A (2020)
Thyroid hormones: As biomarker of preeclampsia and an influencer in outcome of pregnancy
Mukunda Kumar, Sarita Kumari, Vivek Kumar and Amrita Prasad
The literature regarding reports of altered thyroid hormones are lacking in conditions of preeclampsia. The present study was carried out in 100 patients of preeclampsia (50 mild and 50 severe preeclampsia) and 100 normotensive pregnant women (control) admitted or attending the Outpatient Department of Obstetrics and Gynaecology in Nestiva Jay Arogyam Hospital, Patna, in the third trimester of pregnancy (between 28 and 36 weeks). Fifty healthy volunteers served as controls (healthy volunteers comprised of healthy employees of the institute and medical and nursing students). T3 levels were lower in preeclampsia, while Thyroid-stimulating hormone (TSH) and T4 levels were higher in mild preeclampsia as compared with severe preeclampsia. Mean arterial pressure (MAP) was significantly raised in preeclamptic females with higher TSH levels and were also associated with low birth weight. The observations were significant enough to indicate the state of biochemical hypothyroidism that correlates with severity of preeclampsia and influences obstetric outcome in these females.
How to cite this article:
Mukunda Kumar, Sarita Kumari, Vivek Kumar, Amrita Prasad. Thyroid hormones: As biomarker of preeclampsia and an influencer in outcome of pregnancy. Int J Appl Res 2020;6(3):01-03.