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International Journal of Applied Research
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ISSN Print: 2394-7500, ISSN Online: 2394-5869, CODEN: IJARPF

International Journal of Applied Research

Vol. 7, Issue 10, Part C (2021)

Understanding the ANA prevalence and its common pattern in seroconverted dengue infected patients

Author(s)
Deepak Gawali, Vaibhav Misra, Rakesh Gaharwar, Anshu Mittal, Savita Bharat Jain and Rishika Khetan
Abstract
Background: A common complication after viral infection is the onset of autoimmune diseases. Dengue viremia may provoke the immune complex formation in patients who are predisposed to develop autoimmune diseases.
Aim: To assess relation between dengue and autoimmune diseases.
Methodology: A prospective study was conducted over clinically symptomatic dengue patients, who tested positive for IgMAb + NS1 Ag, by examining them after six month duration for presence of IgGAb and ANA and their patterns, using Indirect Immuno fluorescence test (IIFT). Frequency, Mean and standard deviation were calculated, followed by Mann-Whitney U test and Chi square test for categorical data.
Results: 765 cases, among 2249 suspected dengue patients, were found positive for IgM and NS1. After six months, 163 patients were assessed further; out of whom, 120 had developed IgG; while 22 were found ANA positive. Nuclear homogeneous pattern (AC-1) was the most common pattern for ANA Ab.
Conclusion: The patients who are dengue seropositive should be periodically screened for ANA and autoimmune disease development.
Pages: 154-158  |  25 Views  2 Downloads
How to cite this article:
Deepak Gawali, Vaibhav Misra, Rakesh Gaharwar, Anshu Mittal, Savita Bharat Jain, Rishika Khetan. Understanding the ANA prevalence and its common pattern in seroconverted dengue infected patients. Int J Appl Res 2021;7(10):154-158.
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