Vol. 8, Issue 6, Part B (2022)

Abstract
Paraneoplastic syndrome are rare disorders associated with cancers. Among then paraneoplastic cerebellar degeneration is classical PCS, presents acutely and sub acutely with walking incoordination, slurring of voice. Anti YO anti bodies are strongly associated with this PCS. Presence of anti YO antibody shows poor prognosis, and mild recovery with immunosuppressants. Treatment is not very promising in severely affected patient.