Traditional uses, phytochemistry and pharmacology of Embelia ribes Burn: A review
Embelia ribes Burm (Myrsinaceae) has been popularly accepted in traditional medicine for a popular extend of diseases namely sore throat, influenza, tooth pain, pneumonia, headache, carbuncle, abdominal disorders, paralysis, leucoderma, cavities, skin disease, indigestion, constipation, paralysis, convulsions, epilepsy and worm infestation. This objective of the current review is to encompassed the splited fact accessible on the traditional uses, phytochemistry, pharmacology of E. ribes to inquire its beneficial prospective and upcoming research possibilities. All the accessible fact on E. ribes was composed through computerize finding (employing Sci Finder, Pubmed, Scopus and Google Scholar) and a finding of the library. Traditional uses of E. ribes are documented all over India, SriLanka, Singapore, Malaysia and S. China. It is distributed in moist deciduous forests of the Western Ghats of South India, Jammu Kashmir, Himachal Pradesh, Uttar Pradesh, Assam and Maharashtra, where it has been employed for the different types of diseases. The research on bioactive compounds had escort to the seclusion of homoembeline, homorapanone, vilangine, quercitol, Emelicaacid, 2.5% embelin, C18H28O4, Alkaloid (christembine), Resine (embeline) also fixed oil & volatile oil from E. ribes. Bioactive components and extracts of E. ribes expressed a vast extend of pharmacological activities namely analgesic, anti–anxiety, anticonvulsant, antioxidant, neuroprotective, cardioprotective, wound healing, nephroprotective and antidiabetic activity in rat, antihelmintic activity (Pheritima posthuma, Haemonchus contortus, Taenia canina, Phamphistomum cervi ), Antibacterial activity (Bacilus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa) and antifertlity activity. E. ribes arised like substantial provenance of traditional medicine for the cure of different diseases even though different in vivo and in vitro studies authenticated its traditional medicinal uses.