Vol. 9, Special Issue 4, Part A (2023)

Abstract
Cancer has become one of the common occurrences in the modern population and is currently the second paramount cause of mortality worldwide. Most cancer medications and therapies (Chemotherapy/hormonal) used around the world have been reported to have associated side effects. These associated side effects have attracted researchers around the globe towards unearthing molecules from natural sources, with minimal to least side effects. Marine oceans are rich in biodiversity of organisms and their metabolites are unusual from most terrestrial ones due to extreme oceanic conditions. Currently, very few plants and animal-based molecules are used in cancer treatment. This review highlights various recently discovered metabolites and molecules from marine organisms like marine sponges, algae, bacteria, and fungi as potent anti-cancer targets and their potential mechanism of action. These natural molecules for cancer therapy may reduce the predicted and unpredicted side effects caused by most chemical agents used today and point out some potent agents against various cancer types.